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Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dysphagia, and odynophagia complaints, which occurred within 2 weeks after starting dexketoprofen trometamol. An upper endoscopy system examination revealed three well-demarcated ulcers in the esophagus at 35 cm from the incisors. Dexketoprofen trometamol may cause esophageal lesions. This rare disorder should be considered in patients presenting with sudden-onset retrosternal pain in addition to dysphagia and odynophagia.


Sehmus Olmez, Salim Donmez, Mehmet Aslan, Sevdegul Karadas, Alpaslan Yavuz. Esophagitis due to dexketoprofen trometamol: a rare case report. Wiener klinische Wochenschrift. 2015 May;127(9-10):399-401

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PMID: 25412595

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