Development of a Concise Synthetic Approach to Access Oroxin A.

A novel environment-friendly method to access bioactive oroxin A through a one-pot/two-step process from naturally abundant and inexpensive baicalin is described. The procedure presented here has several advantages including clean, one-pot, synthetic ease, and large-scale feasibility. This work also provides a model strategy for rapid and diverse access to natural molecules sharing the common skeleton of this family.

Citation

Haijun Chen, Guihua He, Cailong Li, Longrong Dong, Xiaobo Xie, Jianlei Wu, Yu Gao, Jia Zhou. Development of a Concise Synthetic Approach to Access Oroxin A. RSC advances. 2014 Jan 1;4(85):45151-45154

PMID: 25431654

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