Aminoquinoline based highly sensitive fluorescent sensor for lead(II) and aluminum(III) and its application in live cell imaging.

We have synthesized a new probe 5-((anthracen-9-ylmethylene) amino)quinolin-10-ol (ANQ) based on anthracene platform. The probe was tested for its sensing behavior toward heavy metal ions Hg(2+), Pb(2+), light metal Al(3+) ion, alkali, alkaline earth, and transition metal ions by UV-visible and fluorescent techniques in ACN/H2O mixture buffered with HEPES (pH 7.4). It shows high selectivity toward sensing Pb(2+)/Al(3+) metal ions. Importantly, 10-fold and 5- fold fluorescence enhancement at 429 nm was observed for probe upon complexation with Pb(2+) and Al(3+) ions, respectively. This fluorescence enhancement is attributable to the prevention of photoinduced electron transfer. The photonic studies indicate that the probe can be adopted as a sensitive fluorescent chemosensor for Pb(2+) and Al(3+) ions. Copyright © 2014 Elsevier B.V. All rights reserved.

Citation

Thangaraj Anand, Gandhi Sivaraman, Ayyavu Mahesh, Duraisamy Chellappa. Aminoquinoline based highly sensitive fluorescent sensor for lead(II) and aluminum(III) and its application in live cell imaging. Analytica chimica acta. 2015 Jan 1;853:596-601

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PMID: 25467508

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