Xanthogranulomatous cystitis imitating bladder neoplasm: a case report and review of literature.

Ye Wang, Xiang-Chun Han, Li-Qiang Zheng, Wen-Long Miao

International journal of clinical and experimental pathology 2014

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Xanthogranulomatous cystitis is a rare, benign chronic inflammatory disorder with unclear etiology. Since its similar features to bladder neoplasm, it is extremely easy to be mistaken for malignant tumor. We herein reported a case of xanthogranulomatous cystitis in a 54-year-old male who presented with low abdominal pain and painless, total macrohematuria. Microscopy showed proliferation of large foam histiocytes which expressed CD68 and vimentin. Ki-67 showed a lower proliferation index (< 10%). Histopathology and immunohistochemical findings confirmed the diagnosis. This case highlighted the significance of recognizing this unusual lesion and differentiating it from its histological mimics by immunohistochemical staining.

Citation

Ye Wang, Xiang-Chun Han, Li-Qiang Zheng, Wen-Long Miao. Xanthogranulomatous cystitis imitating bladder neoplasm: a case report and review of literature. International journal of clinical and experimental pathology. 2014;7(11):8255-8