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A reusable inexpensive replacement for dry ice in laboratory use is presented. Commercially available small pellets of stone or metal can be stored in a -80 °C freezer and used for quickly freezing small samples with a freezing rate that is actually somewhat faster than with dry ice itself. Following use, the material is returned to the freezer to re-chill until the next usage. Published by Elsevier Inc.


Tony Ismalaj, Dan L Sackett. An inexpensive replacement for dry ice in the laboratory. Analytical biochemistry. 2015 Apr 1;474:38-9

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PMID: 25617823

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