Sulfogalactosylglycerolipid in spermatogenesis and fertilization].

Xiao Shi, Ting Wang, Song Quan

Zhonghua nan ke xue = National journal of andrology 2015 Feb

filter terms:

Sulfogalactosylglycerolipid (SGG) is the main glycolipid in male mammalian germ cells, which is selectively and highly expressed in mammalian testes and helps form the lipid bilayer of cell membrane. In the process of spermatogenesis, SGG is involved in the meiosis of spermiocytes. Either deficiency or accumulation of SGG will lead to male infertility. SGG homeostasis in the testis is the premise of normal spermatogenesis. In the process of sperm-zona binding, SGG becomes a component of lipid raft and provides a platform for signal transduction. The SGG binding protein plays a role in sperm-egg recognition and membrane fusion. SGG has a great research value and application prospect in male reproduction.

Citation

Xiao Shi, Ting Wang, Song Quan. Sulfogalactosylglycerolipid in spermatogenesis and fertilization]. Zhonghua nan ke xue = National journal of andrology. 2015 Feb;21(2):175-8