Tex10: A New Player in the Core Pluripotency Circuitry.

Revealing how the core pluripotency circuitry is orchestrated to maintain the ground state of embryonic stem cells (ESCs) is fundamental for understanding self-renewal and early lineage specifications. In this issue of Cell Stem Cell, Ding et al. (2015) identify a new Sox2-interacting protein, Tex10, which, together with Tet1 and p300, regulate super-enhancers to sustain pluripotency. Copyright © 2015 Elsevier Inc. All rights reserved.

Citation

Yosef Buganim. Tex10: A New Player in the Core Pluripotency Circuitry. Cell stem cell. 2015 Jun 4;16(6):572-3

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PMID: 26046753

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