Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling.

Christopher C Nawrat, Christopher R Jamison, Yuriy Slutskyy, David W C MacMillan, Larry E Overman

Journal of the American Chemical Society 2015 Sep 9

filter terms:

Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient alkenes is achieved.

Citation

Christopher C Nawrat, Christopher R Jamison, Yuriy Slutskyy, David W C MacMillan, Larry E Overman. Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling. Journal of the American Chemical Society. 2015 Sep 9;137(35):11270-3