Identification of Circulating Tumor Cell（CTC）in Breast Cancer Patients Using a Newly Established CTC Detecting System].

Takuya Nagata, Takashi Ohnaga, Xiao Long Lu, Toru Watanabe, Katsuhisa Hirano, Tomoyuki Okumura, Kazuhiro Tsukada

Gan to kagaku ryoho. Cancer & chemotherapy 2015 Oct

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We developed a new circulating tumor cell (CTC) chip in order to identify CTCs in the peripheral blood of cancer patients. In this study, we aimed to identify CTCs in the blood of breast cancer patients by using this CTC detecting system. In addition, we used this system to evaluate the response to anticancer agents. We were able to identify CTCs in 5 of 6 patients. In addition, the system showed that the number of CTCs had decreased after chemotherapy. Thus, the CTC detecting system was useful in the identification of CTCs in the breast cancer patients and in the early prediction of response to anticancer agents.

Citation

Takuya Nagata, Takashi Ohnaga, Xiao Long Lu, Toru Watanabe, Katsuhisa Hirano, Tomoyuki Okumura, Kazuhiro Tsukada. Identification of Circulating Tumor Cell（CTC）in Breast Cancer Patients Using a Newly Established CTC Detecting System]. Gan to kagaku ryoho. Cancer & chemotherapy. 2015 Oct;42(10):1240-2