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Isonitrile alkylations: a rapid route to imidazo[1,5-a]pyridines.
Chemical communications (Cambridge, England) 2016 Feb 04Sizes of these terms reflect their relevance to your search.
Metalated arylmethylisonitriles readily add to 2-chloropyridines to afford imidazo[1,5-a]pyridines. Analogous additions to imidoyl chlorides and a chloroquinoline provide imidazoles and an imidazo[1,5-a]quinolone which, like imidazo[1,5-a]pyridines, are valuable heterocycles for pharmaceutical synthesis.
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Yajun Li, Allen Chao, Fraser F Fleming. Isonitrile alkylations: a rapid route to imidazo[1,5-a]pyridines. Chemical communications (Cambridge, England). 2016 Feb 04;52(10):2111-3
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PMID: 26691391
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