Sachiko Kashojiya, Shizue Yoshihara, Koji Okajima, Satoru Tokutomi
FEBS letters 2016 JanPhototropin (phot), a blue light receptor in plants, is composed of several domains: LOV1, LOV2, and a serine/threonine kinase (STK). LOV2 is the main regulator of light activation of STK. However, the detailed mechanism remains unclear. In this report, we focused on the linker region between LOV2 and STK excluding the Jα-helix. Spectroscopy and a kinase assay for the substituents in the linker region of Arabidopsis phot1 LOV2-STK indicated that the linker is involved in the activation of STK. A putative module in the middle of the linker would be critical for intramolecular signaling and/or regulation of STK. © 2015 Federation of European Biochemical Societies.
Sachiko Kashojiya, Shizue Yoshihara, Koji Okajima, Satoru Tokutomi. The linker between LOV2-Jα and STK plays an essential role in the kinase activation by blue light in Arabidopsis phototropin1, a plant blue light receptor. FEBS letters. 2016 Jan;590(1):139-47
PMID: 26763121
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