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Angioedema is a deep intradermal or sub-cutaneous edema, which can be mediated by histamine, bradykinin or mixture of both components. The aims of this review are to describe the clinical approach and diagnosis of non-hereditary bradykinin-mediated angioedema induced by drugs such as: angiotensin-converting inhibitor, sartan, gliptins, rapamycin or some thrombolytic reagents and renin inhibitors. Furthermore, we will discuss the drug management of these angioedema, which is mainly based on C1 inhibitor concentrate or icatibant administration.

Citation

Yannick Muller, Thomas Harr. Treatment of drugs-associated non-hereditary angioedema mediated by bradykinin]. Revue médicale suisse. 2016 Jan 13;12(500):11-2

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PMID: 26946694

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