Characterisation of mitochondrial haplotypes occurred in a Candida albicans population.

The genetic background of mitochondrial DNA polymorphism in Candida albicans was studied by physical and functional mapping of four haplotypes identified recently in a hospital-population. The restriction patterns revealed considerable differences; however, the size of the mitochondrial DNA did not vary significantly. Sequence data demonstrated that size differences arose by short deletions, while restriction fragment length polymorphisms are caused by nucleotide substitutions in single sites. Gene rearrangement could not be detected; nevertheless, the coincidence of nucleotide substitution pattern in the inverted repeat region suggested the occurrence of homologue recombination.

Citation

Ilona Pfeiffer, Zoltán Farkas, Judit Kucsera, Muthusamy Chandrasekaran, Shine Kadaikunnan, Naiyf S Alharbi, Csaba Vágvölgyi. Characterisation of mitochondrial haplotypes occurred in a Candida albicans population. Acta biologica Hungarica. 2016 Mar;67(1):112-20

Mesh Tags

Substances

PMID: 26960361

search → result