Acetophenones Isolated from Acronychia pedunculata and their Anti-proliferative Activities.

Chihiro Ito, Takuya Matsui, Yoshiaki Ban, Tian-Shung Wu, Masataka Itoigawa

Natural product communications 2016 Jan

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Study of the chemical constituents of Acronychia pedunculata (L.) Miq. (Rutaceae) stems collected in Taiwan led to the isolation and identification of eight known and three new acetophenones, named acrophenone A (1), B (2), and C (3). Of them, acrovestone (5), acropyrone (6) and acrovestenol (7), which are dimer compounds, strikingly inhibited the proliferation of human leukemia cell lines.

Citation

Chihiro Ito, Takuya Matsui, Yoshiaki Ban, Tian-Shung Wu, Masataka Itoigawa. Acetophenones Isolated from Acronychia pedunculata and their Anti-proliferative Activities. Natural product communications. 2016 Jan;11(1):83-6