Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C-H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.
Chengwei Zhang, Lin You, Chuo Chen. Palladium-Catalyzed C-H Arylation of 1,2,3-Triazoles. Molecules (Basel, Switzerland). 2016 Sep 22;21(10)
PMID: 27669198
View Full Text