Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Fibrillarin is one of the most studied nucleolar proteins. Its main functions are methylation and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course of evolution from archaea to eukaryotes, it acquired an additional N-terminal glycine and arginine-rich (GAR) domain. In this review, we discuss the evolution of fibrillarin structure and its relation to the functions of the protein in prokaryotes and eukaryotes.


M Y Shubina, Y R Musinova, E V Sheval. Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions. Biochemistry. Biokhimiia. 2016 Sep;81(9):941-50

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 27682166

View Full Text