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Selective estrogen receptor modulators(SERMs), or estrogen receptor agonists/antagonists(ERAAs), are a class of compounds that function as estrogen receptor(ER)agonists or antagonists tissue-dependently. Two types of SERMs are currently used in Japan to treat osteoporosis, raloxifene(RLX:Evista)and bazedoxifene(BZA:Viviant). This article describes the pharmacokinetics of these two drugs.


Masakazu Terauchi. Pharmacokinetics of selective estrogen receptor modulators(SERMs). Clinical calcium. 2016;26(11):1571-1581

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PMID: 27777390

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