Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori.

Dopa decarboxylase (DDC) protein is involved in the synthesis of dopamine and serotonin. Here, we show that in the silkworm Bombyx mori, a novel DDC splicing variant is selectively expressed in the brain and subesophageal ganglia. In Drosophila melanogaster, a neuron-specific isoform of DDC is known to be alternatively spliced in a similar manner.

Citation

Dai Tsukioka, Susumu Izumi, Takeshi Adachi. Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori. Bioscience, biotechnology, and biochemistry. 2017 Mar;81(3):555-557

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PMID: 27869544

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