Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori.

Dai Tsukioka, Susumu Izumi, Takeshi Adachi

Bioscience, biotechnology, and biochemistry 2017 Mar

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Dopa decarboxylase (DDC) protein is involved in the synthesis of dopamine and serotonin. Here, we show that in the silkworm Bombyx mori, a novel DDC splicing variant is selectively expressed in the brain and subesophageal ganglia. In Drosophila melanogaster, a neuron-specific isoform of DDC is known to be alternatively spliced in a similar manner.

Citation

Dai Tsukioka, Susumu Izumi, Takeshi Adachi. Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori. Bioscience, biotechnology, and biochemistry. 2017 Mar;81(3):555-557