Flavonol glycosides from the leaves of Elaeagnus pungens.

Ying-Ying Shang, Qin Qin, Meng-Shun Li, Hai-Yan Xu, Yue-Bin Ge

Natural product research 2017 May

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The leaves of Elaeagnus pungens were extracted and successively purified by a set chromatographic techniques. The structures of the obtained constituents were elucidated on the basis of spectroscopic methods including 1D/2D NMR and high resolution-MS. One new flavonoid glycosides, kaempferol 3-O-β-d-glucopyranosyl-(1 → 3)-α-l-rhamnopyranosyl-(1 → 6)-[α-l-rhamnopyranosyl(1 → 2)]-β-d-galactopyranoside-7-O-β-d-glucopyranoside (1), along with five known compounds (2-6) were isolated and identified. The MTT assay in vitro showed that the isolated flavonol glycosides have no proliferating activity, suggesting no aggravating impact on the increased airway smooth muscle cells.

Citation

Ying-Ying Shang, Qin Qin, Meng-Shun Li, Hai-Yan Xu, Yue-Bin Ge. Flavonol glycosides from the leaves of Elaeagnus pungens. Natural product research. 2017 May;31(9):1066-1072