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Recent studies found that peripapillary microcirculation was damaged in glaucoma patients, indicating that blood flow in the optic nerve head is important in the pathogenesis of glaucoma. Effects of different antiglaucoma drugs on optic papilla blood flow deserve attention. Prostaglandins is the first line antiglaucoma drug. The experimental and clinical studies on the potential of prostaglandins to modify the blood flow in the optic papilla and related mechanisms are reviewed in this article. Effects of ocular blood flow increase on the treatment of glaucoma require further investigations. (Chin J Ophthalmol, 2017, 53: 73-76).


S H Zhang, J L Zhao. Prostaglandins and optic papilla blood flow]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 2017 Jan 11;53(1):73-76

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PMID: 28162202

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