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CKMT1 May Be a Therapeutic Target in EVI1-Driven Acute Myeloid Leukemia.
Cancer discovery 2017 Apr
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CKMT1 is highly expressed in EVI1-positive AML cells and promotes their growth in vitro and in vivo. ©2017 American Association for Cancer Research.
Citation
CKMT1 May Be a Therapeutic Target in EVI1-Driven Acute Myeloid Leukemia.
Cancer discovery.
2017 Apr;7(4):349
Mesh Tags
Animals
Cell Line, Tumor
Creatine Kinase
DNA-Binding Proteins
Gene Expression Regulation, Leukemic
Humans
Leukemia, Myeloid, Acute
MDS1 and EVI1 Complex Locus Protein
Mice
Molecular Targeted Therapy
Xenograft Model Antitumor Assays
Substances
DNA-Binding Proteins
MDS1 and EVI1 Complex Locus Protein
MECOM protein, human
CKMT1A protein, human
Creatine Kinase
PMID: 28235853
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