Pediatric Liver Transplant For Hepatoblastoma: A Single-Center Experience.

Our aim was to analyze our experience with orthotopic liver transplant for hepatoblastoma patients. We performed a single-center retrospective analysis of 6 orthotopic liver transplant cases in children with hepatoblastoma from 2001 to March 2015. We evaluated patient demographic features, pretreatment extent of disease stage, type of transplant, change in serum alpha-fetoprotein levels, complications, and follow-up results. Orthotopic liver transplant was performed for pretreatment extent of disease stage III with a central location (n = 3) and pretreatment extent of disease stage IV (n = 3). All children underwent living-donor orthotopic liver transplant. Postoperative serum alpha-fetoprotein levels remained below 10 ng/mL during the follow-up period in 3 patients who were free of recurrences or metastases. Five patients were free of tumor recurrences at a median follow-up of 29.9 months. The limited number of cases we present without long-term follow-up of orthotopic liver transplant for unresectable hepatoblastoma seemed to show good clinical results.

Citation

Mahir Kirnap, Ebru Ayvazoglu Soy, Figen Ozcay, Gokhan Moray, Binnaz Handan Ozdemir, Mehmet Haberal. Pediatric Liver Transplant For Hepatoblastoma: A Single-Center Experience. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 2017 Feb;15(Suppl 1):50-52

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PMID: 28260432

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