New insights into protein secretion: TANGO1 runs rings around the COPII coat.

In this issue, Liu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201611088) and Raote et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608080) use super-resolution microscopy to visualize large COPII-coated endoplasmic reticulum (ER) export carriers. Rings of TANGO1 surround COPII, implicating TANGO1 in organizing ER exit sites and in regulating COPII coat dynamics and geometry. © 2017 Glick.

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Benjamin S Glick. New insights into protein secretion: TANGO1 runs rings around the COPII coat. The Journal of cell biology. 2017 Apr 03;216(4):859-861

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PMID: 28292851

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