Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2.

Mariia V Sutton, Matthew McKinley, Revathy Kulasekharan, Vladimir V Popik

Chemical communications (Cambridge, England) 2017 May 18

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A new photocleavable analog of BAPTA chelating ligand has a high affinity towards Ca2+ ions (K = 2.5 × 106 M-1). The use of photolabile 3-(hydroxymethyl)-2-naphthol core in the design of photo-BAPTA allows for the efficient (Φ = 0. 63) and very fast (τ < 12 μs) release of Ca2+ ions upon 300 or 350 nm irradiation.

Citation

Mariia V Sutton, Matthew McKinley, Revathy Kulasekharan, Vladimir V Popik. Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2. Chemical communications (Cambridge, England). 2017 May 18;53(41):5598-5601

PMID: 28393957

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