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Formation of membrane discs in photoreceptor cells requires evagination of its ciliary plasma membrane by an unknown molecular mechanism. Salinas et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608081) show that peripherin (also known as peripherin-2 or peripherin-2/rds) diverts membrane traffic to photoreceptor disc formation by inhibiting ectosome release from the cilium. © 2017 Molday and Goldberg.

Citation

Robert S Molday, Andrew F X Goldberg. Peripherin diverts ciliary ectosome release to photoreceptor disc morphogenesis. The Journal of cell biology. 2017 May 01;216(5):1227-1229

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PMID: 28400442

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