Current Status of Dengue Therapeutics Research and Development.

Jenny G H Low, Eng Eong Ooi, Subhash G Vasudevan

The Journal of infectious diseases 2017 Mar 01

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Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of dengue. This review will provide a brief account of the status of therapeutics research and development for dengue. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.

Citation

Jenny G H Low, Eng Eong Ooi, Subhash G Vasudevan. Current Status of Dengue Therapeutics Research and Development. The Journal of infectious diseases. 2017 Mar 01;215(suppl_2):S96-S102