Dalmatian: spotting the difference in cohesin protectors.

Adele L Marston

The EMBO journal 2017 Jun 01

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The cohesin complex prevents separation of chromosomes following their duplication until the appropriate time during cell division. In vertebrates, establishment and maintenance of cohesin-dependent linkages depend on two distinct proteins, sororin and shugoshin. New findings published in The EMBO Journal show that in Drosophila, the function of both of these cohesin regulators is carried out by a single hybrid protein, Dalmatian. © 2017 The Author.