A DNA modification-methylation of cytosines and adenines-has important roles in diverse processes such as regulation of gene expression and genome stability, yet until recently adenine methylation had been considered to be only a hallmark of prokaryotes. A new study identifies abundant adenine methylation of transcriptionally active genes in early-diverging fungi that, together with recent other work, emphasizes the importance of adenine methylation in eukaryotes.
Citation
Michael F Seidl. Adenine N6-methylation in diverse fungi. Nature genetics. 2017 May 26;49(6):823-824
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PMID: 28546576
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