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Many strategies have been explored for selectively and sensitively detecting cysteine in different samples. Here, a novel colorimetric sensor based on self-assembly nanostructures of Fe3+-H2O2/Tetramethylbenzidine system with dual-level logic gate function and colorimetric determination of cysteine were firstly explored. The proposed Fe3+-H2O2-TMB system provides a sensitive optical signal due to the selectively reductive ability of cysteine to the oxidized TMB and thus could be successfully applied to the construction of instant on-site visual detection method with a paper based test strip for cysteine determination in a sample solution as well as for a dual-level logic gate fabrication. Copyright © 2017 Elsevier Inc. All rights reserved.

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Zhonghua Xue, Xiaofen Wang, Honghong Rao, Xiuhui Liu, Xiaoquan Lu. A colorimetric sensor of cysteine based on self-assembly nanostructures of Fe3+-H2O2/Tetramethylbenzidine system with "On-Off" switching function. Analytical biochemistry. 2017 Oct 01;534:1-9

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PMID: 28693991

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