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In this issue of Developmental Cell, Nguyen et al. (2017) show that lipid droplets serve a dual purpose during starvation. First, they act as an energy source by supplying fatty acids for mitochondrial β oxidation. Second, they sequester toxic lipids that arise during autophagic degradation of membranous organelles, thereby protecting mitochondria. Copyright © 2017 Elsevier Inc. All rights reserved.
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Till Klecker, Ralf J Braun, Benedikt Westermann. Lipid Droplets Guard Mitochondria during Autophagy. Developmental cell. 2017 Jul 10;42(1):1-2
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PMID: 28697329
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