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Put Your Mark Where Your Damage Is: Acetyl-CoA Production by ACLY Promotes DNA Repair.
Molecular cell 2017 Jul 20Sizes of these terms reflect their relevance to your search.
In this issue of Molecular Cell, Sivanand et al. (2017) describe the importance for nuclear ACLY-mediated production of acetyl-CoA, which promotes histone acetylation, BRCA1 recruitment, and subsequent HR-mediated DNA repair in response to DNA damage, thus drawing a direct link between DNA repair and cellular metabolism. Copyright © 2017 Elsevier Inc. All rights reserved.
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Samantha J Linder, Raul Mostoslavsky. Put Your Mark Where Your Damage Is: Acetyl-CoA Production by ACLY Promotes DNA Repair. Molecular cell. 2017 Jul 20;67(2):165-167
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PMID: 28732204
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