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Tumour proteostasis and the unfolded protein response (UPR) are emerging drivers of tumour progression and important determinants of clinical efficacy of cancer therapy. Recent findings indicate that they also regulate the production of protein tumour markers. Here, we discuss how this new knowledge opens up new perspectives for cancer therapeutics. Copyright © 2016 Elsevier Inc. All rights reserved.

Citation

Antoine Galmiche, Chloé Sauzay, Aline Houessinon, Bruno Chauffert, Olivier Pluquet. Probing Tumour Proteostasis and the UPR with Serum Markers. Trends in cancer. 2016 May;2(5):219-221


PMID: 28741509

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