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Research on cupping therapy is lacking at home and abroad. However, cupping and acupuncture therapy are both surface stimulation therapies. This paper suggests the mechanism of cupping therapy and proposes that the same mechanism underlies both cupping and acupuncture therapy. The microenvironment is changed when stimulating the surface of the skin, and physical signals transform into biological signals, which also interact with each other in the body. These signalling cascades activate the neuroendocrine-immune system, which produces the therapeutic effect. Copyright © 2017 Elsevier Ltd. All rights reserved.


Yang Guo, Bo Chen, Dong-Qiang Wang, Ming-Yue Li, Calista Hui-Min Lim, Yi Guo, Zelin Chen. Cupping regulates local immunomodulation to activate neural-endocrine-immune worknet. Complementary therapies in clinical practice. 2017 Aug;28:1-3

PMID: 28779915

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