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Incorporating each set of daughter chromosomes into a single nucleus at the end of mitosis is essential for genome stability. In a recent Cell paper, Samwer et al. (2017) show that by non-covalently crosslinking DNA, BAF promotes chromosome coalescence, preventing nuclear membranes from enwrapping individual chromosomes to form micronuclei. Copyright © 2017 Elsevier Inc. All rights reserved.
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Mingxuan Sun, Rebecca Heald. A DNA Crosslinker Collects Mitotic Chromosomes. Developmental cell. 2017 Sep 11;42(5):440-442
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PMID: 28898675
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