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The Negative Regulator CXXC5: Making WNT Look a Little Less Dishevelled.
Dongwon Kim, Luis A Garza
The Journal of investigative dermatology 2017 Nov
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Wingless-related integration site (WNT)/β-catenin signaling regulates diverse physiological functions including tissue regeneration. Activation of WNT signaling can be inhibited by various agents. Lee et al. investigate the interaction of CXXC-type zinc finger protein 5 (CXXC5) with Dishevelled as one such negative regulator of WNT in hair follicle regeneration. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
Citation
Dongwon Kim, Luis A Garza.
The Negative Regulator CXXC5: Making WNT Look a Little Less Dishevelled.
The Journal of investigative dermatology.
2017 Nov;137(11):2248-2250
Mesh Tags
Alopecia
Animals
Carrier Proteins
Gene Expression Regulation
Hair Follicle
Humans
Intracellular Signaling Peptides and Proteins
Mice
Regeneration
Sensitivity and Specificity
Signal Transduction
Valproic Acid
Wnt Proteins
Wnt Signaling Pathway
beta Catenin
Substances
CXXC5 protein, human
CXXC5 protein, mouse
Carrier Proteins
Intracellular Signaling Peptides and Proteins
Wnt Proteins
beta Catenin
Valproic Acid
PMID: 28967390
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