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Wingless-related integration site (WNT)/β-catenin signaling regulates diverse physiological functions including tissue regeneration. Activation of WNT signaling can be inhibited by various agents. Lee et al. investigate the interaction of CXXC-type zinc finger protein 5 (CXXC5) with Dishevelled as one such negative regulator of WNT in hair follicle regeneration. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Citation

Dongwon Kim, Luis A Garza. The Negative Regulator CXXC5: Making WNT Look a Little Less Dishevelled. The Journal of investigative dermatology. 2017 Nov;137(11):2248-2250

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PMID: 28967390

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