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    Periana argues that the stepwise reaction of methane with water is thermodynamically unfavorable and therefore impractical. We reply by presenting an in-depth thermodynamic analysis of each step in the process and show that the surface concentrations of the reactants and products as well as the stabilizing effect of additional water molecules, as discussed in the original paper, fully support the feasibility of the proposed reaction. Copyright © 2017, American Association for the Advancement of Science.

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    Vitaly L Sushkevich, Dennis Palagin, Marco Ranocchiari, Jeroen A van Bokhoven. Response to Comment on "Selective anaerobic oxidation of methane enables direct synthesis of methanol". Science (New York, N.Y.). 2017 Oct 13;358(6360)

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    PMID: 29026017

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