Spirooxindoles as Potential Pharmacophores.

Siva S Panda, Rachel A Jones, Praveen Bachawala, Prabhu P Mohapatra

Mini reviews in medicinal chemistry 2017

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The spirooxindole heterocyclic scaffold is found in many natural products and has been identified as an important bioactive agent. Over the past few decades, various spirooxindole-containing compounds have been reported to possess biological properties and hence found in the structure of many synthetic pharmaceuticals. This mini-review describes the most promising examples of this class of compounds possessing biological activity including anticancer, anti-inflammatory, and antimicrobial activities. The current review focuses on the biological activity of compounds containing the spirooxindole scaffold. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Citation

Siva S Panda, Rachel A Jones, Praveen Bachawala, Prabhu P Mohapatra. Spirooxindoles as Potential Pharmacophores. Mini reviews in medicinal chemistry. 2017;17(16):1515-1536