Gastric adenocarcinoma of fundic gland type spreading to heterotopic gastric glands.

Herein, we present a case of gastric adenocarcinoma of fundic gland type (GA-FG) spreading to heterotopic gastric glands (HGG) in the submucosa. A 58-year-old man with epigastric pain was referred to our hospital and underwent an esophagogastroduodenoscopy. A Borrmann type II gastric cancer at the antrum and a 10 mm submucosal tumor-like lesion in the lesser curvature of the upper third of the stomach were detected. Histological examination of the biopsy specimens obtained from the submucosal tumor-like lesion suggested a GA-FG. Therefore, endoscopic submucosal dissection was performed as excisional biopsy, and histopathological examination of the resected specimen confirmed a GA-FG and HGG proximal to the GA-FG. Although the GA-FG invaded the submucosal layer slightly, the submucosal lesion of the GA-FG had a poor stromal reaction and was located just above the HGG in the submucosa. Therefore, we finally diagnosed the lesion as a GA-FG invading the submucosal layer by spreading to HGG.

Citation

Shigeo Manabe, Ken-Ichi Mukaisho, Takayuki Yasuoka, Fumitaka Usui, Tatsuzo Matsuyama, Ikuhiro Hirata, Yoshio Boku, Shuji Takahashi. Gastric adenocarcinoma of fundic gland type spreading to heterotopic gastric glands. World journal of gastroenterology. 2017 Oct 14;23(38):7047-7053

PMID: 29097877

search → result