Functional Amyloid and Other Protein Fibers in the Biofilm Matrix.

Elliot Erskine, Cait E MacPhee, Nicola R Stanley-Wall

Journal of molecular biology 2018 Oct 12

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Biofilms are ubiquitous in the natural and man-made environment. They are defined as microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing evidence from the genetic and biochemical analysis of single species biofilms has linked the presence of fibrous proteins to a functional biofilm matrix. Some of these fibers have been described as functional amyloid or amyloid-like fibers. Here we provide an overview of the biophysical and biological data for a wide range of protein fibers found in the biofilm matrix of Gram-positive and Gram-negative bacteria. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Citation

Elliot Erskine, Cait E MacPhee, Nicola R Stanley-Wall. Functional Amyloid and Other Protein Fibers in the Biofilm Matrix. Journal of molecular biology. 2018 Oct 12;430(20):3642-3656