CYP2E1 activity and children with obesity: possible confounding factors.

Hardeep Kaur, Phulen Sarma, Ajay Prakash, Bikash Medhi

British journal of clinical pharmacology 2019 Feb

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Lots of factors can influence CYP2E1 activities, e.g. thyroid status, different types of anaemia (fanconi anaemia and sideroblastic anaemia), etc. Alcohol is a known inducer of CYP2E1, therefore a justifiable duration of abstinence is required before the subjects are enrolled into a study for normalization of CYP2E1 activity. In this letter we address these confounding factors and their role in CYP2E1 activity. © 2018 The British Pharmacological Society.

Citation

Hardeep Kaur, Phulen Sarma, Ajay Prakash, Bikash Medhi. CYP2E1 activity and children with obesity: possible confounding factors. British journal of clinical pharmacology. 2019 Feb;85(2):457