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CAPAM: The mRNA Cap Adenosine N6-Methyltransferase.

Victoria H Cowling

Trends in biochemical sciences 2019 Mar


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    The mRNA cap is a structure that protects mRNA from degradation and recruits processing and translation factors. A new mRNA capping enzyme has been identified, PCIF1/CAPAM, which methylates adenosine when it is the first transcribed nucleotide. This discovery is crucial for understanding the function of cap adenosine methylation. Copyright © 2019 The Author. Published by Elsevier Ltd.. All rights reserved.

    Citation

    Victoria H Cowling. CAPAM: The mRNA Cap Adenosine N6-Methyltransferase. Trends in biochemical sciences. 2019 Mar;44(3):183-185

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    PMID: 30679132

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