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Small cell carcinoma of ovary, hypercalcemic type is a rare malignancy with a dismal prognosis. The diagnosis is often confused with many other tumors. We describe a rare case of ovarian small cell carcinoma of hypercalcemic type in an adolescent. She presented with abdominal pain, awareness of mass and vomiting. She underwent exploratory laparotomy and right ovarian excision. The detailed histopathological examination including immunohistochemistry was suggestive of ovarian small cell carcinoma of hypercalcemic type. She had progressive disease on chemotherapy and ultimately died within 2 years of diagnosis. Due to rarity of this neoplasm and its aggressive nature, the optimal treatment regimen has not been established. We report this case because of its rare occurrence leading to clinical and diagnostic challenges and need to explore effective treatment options to improve survival in these patients.


Divya Khosla, Nalini Gupta, Abin Koshy, Ashwani Dalal, A K Pandey, Kislay Dimri. Ovarian Small Cell Carcinoma of Hypercalcemic Type in an Adolescent Girl. Journal of obstetrics and gynaecology of India. 2019 Apr;69(Suppl 1):60-62

PMID: 30956495

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