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Simultaneous delivery of gene and chemotherapeutics via copolymeric micellar nanoparticles to overcome multiple drug resistance to promote synergistic tumor suppression.
Jianguo Gao, Lingxiao Chen, Ruogu Qi, Zhihua Zhou, Zaian Deng, Jue Shi, Tao Qin, Shengzhe Zhao, Yuna Qian, Jianliang Shen
Journal of biomaterials applications 2019 Jul
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Citation
Jianguo Gao, Lingxiao Chen, Ruogu Qi, Zhihua Zhou, Zaian Deng, Jue Shi, Tao Qin, Shengzhe Zhao, Yuna Qian, Jianliang Shen.
Simultaneous delivery of gene and chemotherapeutics via copolymeric micellar nanoparticles to overcome multiple drug resistance to promote synergistic tumor suppression.
Journal of biomaterials applications.
2019 Jul;34(1):130-140
Mesh Tags
Antibiotics, Antineoplastic
Cell Line, Tumor
Cell Membrane Permeability
Cholesterol
Combined Modality Therapy
Doxorubicin
Drug Liberation
Drug Resistance, Multiple
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic
Gene Silencing
Humans
Hydrophobic and Hydrophilic Interactions
Lymphoma, B-Cell
Micelles
Nanocapsules
Polyesters
Polyethylene Glycols
Polylysine
Proto-Oncogene Proteins c-bcl-2
RNA, Small Interfering
RNAi Therapeutics
Transfection
Substances
(O-methylpoly(ethylene glycol)-O'-succinyl)-N-epsilon-poly(L-lysine)
Antibiotics, Antineoplastic
Micelles
Nanocapsules
Polyesters
Proto-Oncogene Proteins c-bcl-2
RNA, Small Interfering
methoxy poly(ethylene glycol)-b-poly(epsilon-caprolactone)-b-poly(L-lysine)
polycaprolactone
Polylysine
Polyethylene Glycols
Doxorubicin
Cholesterol
PMID: 30971178
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