BRCA1/2 Variant Data-Sharing Practices.

Accessing BRCA1/2 data facilitates the detection of disease-associated variants, which is critical to informing clinical management of risks. BRCA1/2 data sharing is complex and many practices exist. We describe current BRCA1/2 data-sharing practices, in the United States and globally, and discuss obstacles and incentives to sharing, based on 28 interviews with personnel at U.S. and non-U.S. clinical laboratories and databases. Our examination of the BRCA1/2 data-sharing landscape demonstrates strong support for and robust sharing of BRCA1/2 data around the world, increasing global accesses to diverse data sets.

Citation

Juli M Bollinger, Abhi Sanka, Lena Dolman, Rachel G Liao, Robert Cook-Deegan. BRCA1/2 Variant Data-Sharing Practices. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics. 2019 Mar;47(1):88-96

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PMID: 30994073

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