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Senescence Evasion in Chemotherapy: A Sweet Spot for p21.

Humza M Ashraf, Justin Moser, Sabrina L Spencer

Cell 2019 Jul 11


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  • cell cycle (2)
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    Time-lapse imaging reveals a nuanced role for p21 in cancer cells challenged with chemotherapeutic drugs: cells with either high or low p21 are biased toward senescence, whereas intermediate p21 allows cells to re-enter the cell cycle after drug treatment. Copyright © 2019 Elsevier Inc. All rights reserved.

    Citation

    Humza M Ashraf, Justin Moser, Sabrina L Spencer. Senescence Evasion in Chemotherapy: A Sweet Spot for p21. Cell. 2019 Jul 11;178(2):267-269

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    PMID: 31299197

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