Three new flavonoids from Penthorum chinense Pursh and their docking studies.

Three new flavonoids, pinocembrin-7-O-[3″-O-galloyl]-β-D-glucose (1), pinocembrin-7-O-[2″-O-galloyl-4″,6″-hexahydroxydiphenoyl]-β-D-glucose (2), 2',6'-dihydroxydihydrochalcone-4'-O-[2″-O-galloyl-4″,6″-hexahydroxydiphenoyl]-β-D-glucopyranoside (3), and 12 known compounds (4-15) were isolated from Penthorum Chinense Pursh. The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. The anti-hyperlipidemic activities of the three new flavonoids were predicted by molecular docking.

Citation

Wen-Wen Zhao, Wei-Wei Guo, Jun-Fang Guo, Xing Wang, Xiao-Qing Chen, Xia Wu. Three new flavonoids from Penthorum chinense Pursh and their docking studies. Natural product research. 2021 Jan;35(1):49-56

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PMID: 31342796

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