A Comprehensive Review on the Therapeutic Versatility of Imidazo [2,1-b]thiazoles.

Imidazo[2,1-b]thiazole, a well-known fused five-membered hetrocycle is one of the most promising and versatile moieties in the area of medicinal chemistry. Derivatives of imidazo[2,1-b]thiazole have been investigated for the development of new derivatives that exhibit diverse pharmacological activities. This fused heterocycle is also a part of a number of therapeutic agents. To review the extensive pharmacological activities of imidazo[2,1-b]thiazole derivatives and the new molecules developed between 2000-2018 and their usefulness. Thorough literature review of all relevant papers and patents was conducted. The present review, covering a number of aspects, is expected to provide useful insights in the design of imidazo[2,1-b]thiazole-based compounds and would inspire the medicinal chemists for a comprehensive and target-oriented information to achieve a major breakthrough in the development of clinically viable candidates. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Citation

Mohd Adil Shareef, Irfan Khan, Bathini Nagendra Babu, Ahmed Kamal. A Comprehensive Review on the Therapeutic Versatility of Imidazo [2,1-b]thiazoles. Current medicinal chemistry. 2020;27(40):6864-6887

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PMID: 31362648

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