Polymer Nanocontainers for Intracellular Delivery.

Carriers for intracellular delivery are required to overcome limitations of therapeutic agents such as low specificity, systemic toxicity, high clearance rate, and low therapeutic index. Nanocontainers comprised of an aqueous core and a polymer shell have received increasing attention because they readily combine stimuli response to improve intracellular payload release and surface modification to enhance selectivity towards the desired region of action. This Minireview summarizes the design and properties of polymer nanocontainers for intracellular delivery, classified according to the polymer architecture. © 2019 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Citation

Sharafudheen Pottanam Chali, Bart Jan Ravoo. Polymer Nanocontainers for Intracellular Delivery. Angewandte Chemie (International ed. in English). 2020 Feb 17;59(8):2962-2972

Mesh Tags

Substances

PMID: 31364243

search → result