Replication complexes of (+)RNA viruses of eukaryotes are associated with specialized membranous domains, termed replication organelles. How these structures develop is poorly understood. In a recent Cell paper, Laufman et al. (2019) reveal that enteroviruses recruit lipid droplets to support lipid synthesis required for the structural development of replication organelles. Copyright © 2019 Elsevier Inc. All rights reserved.
George A Belov, Frank J M van Kuppeveld. Lipid Droplets Grease Enterovirus Replication. Cell host & microbe. 2019 Aug 14;26(2):149-151
PMID: 31415743
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