The activity of stem cells in the adult brain is controlled by various niche-dependent mechanisms. A new article by Lepko et al (2019) shows that proliferation of neural stem cells in the ventricular-subventricular zone is regulated by choroid plexus-derived miR-204, identifying a novel mechanism of how the delicate balance between stem cell quiescence and activation is controlled. © 2019 The Authors.
Thomas Wegleiter, Sebastian Jessberger. Sleep or deplete: how the choroid plexus helps to keep neural stem cells in balance. The EMBO journal. 2019 Sep 02;38(17):e103013
PMID: 31432524
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